Can I use a different type of chip instead of Doritos?

Yes! While Nacho Cheese Doritos give the best flavor, you can also use: Cool Ranch Doritos (adds a tangy flavor) Tortilla Chips (for a more traditional taste) Fritos (for extra crunch)

Is this casserole spicy?

It depends on the ingredients used. To adjust the spice level: For a mild version: Use regular Rotel and no jalapeños . For a spicier version: Use hot Rotel, spicy taco seasoning, and extra jalapeños .

Can I make this casserole ahead of time?

Yes! You can prepare the casserole up to 24 hours in advance : Assemble it without the top layer of Doritos and store it covered in the fridge. Add fresh Doritos and bake when ready.

What’s the best way to reheat leftovers?

Oven: Bake at 350°F for 15–20 minutes for the best texture. Microwave: Heat in 30-second intervals , but note that the Doritos may become soft.

Can I make a vegetarian version?

Yes! Simply swap out the chicken for: Black beans Lentils Sautéed bell peppers and mushrooms

What’s the best cheese to use?

A blend of cheddar, Monterey Jack, and pepper jack works best for maximum creaminess and flavor .

Can I freeze this casserole?

Yes! Assemble the casserole without the Doritos on top , wrap it well, and freeze for up to 2 months . Thaw overnight in the fridge, then add fresh Doritos before baking.

Best Mexican Chicken Casserole with Doritos

Name: Best Mexican Chicken Casserole with Doritos – Easy & Cheesy Recipe
Prep time: 10 min
Cook time: 30 min
Total time: 40 min
Cuisine: Mexican
Ingredients: 3 cups cooked shredded chicken; 1 (10.5 oz) can cream of chicken soup; 1 cup sour cream; 1 cup salsa (mild, medium, or hot, depending on preference); 1 (10 oz) can Rotel diced tomatoes and green chilies, drained; 1 teaspoon taco seasoning; 2 cups shredded Mexican blend cheese, divided; 1 (9.75 oz) bag nacho cheese Doritos, crushed; ¼ cup chopped fresh cilantro (optional, for garnish)

Description

This Mexican Chicken Casserole with Doritos is a cheesy, creamy, and flavor-packed dish that’s easy to make and delicious. Made with tender shredded chicken, a creamy salsa-infused sauce, and crunchy nacho cheese Doritos, this casserole is the ultimate comfort food with a Tex-Mex twist. It’s perfect for busy weeknights or potlucks, and the whole family will love it!

Ingredients

Scale

3 cups cooked shredded chicken
1 (10.5 oz) can cream of chicken soup
1 cup sour cream
1 cup salsa (mild, medium, or hot, depending on preference)
1 (10 oz) can Rotel diced tomatoes and green chilies, drained
1 teaspoon taco seasoning
2 cups shredded Mexican blend cheese, divided
1 (9.75 oz) bag nacho cheese Doritos, crushed
¼ cup chopped fresh cilantro (optional, for garnish)

Instructions

Preheat your oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.
Crush the Doritos into bite-sized pieces and spread half of them evenly on the bottom of the baking dish.
In a large bowl, mix the shredded chicken, cream of chicken soup, sour cream, salsa, Rotel tomatoes, taco seasoning, and 1 cup of shredded cheese until well combined.
Spread the chicken mixture evenly over the Doritos layer in the baking dish.
Top with the remaining crushed Doritos and sprinkle the remaining 1 cup of shredded cheese over the top.
Bake uncovered for 25–30 minutes or until the cheese is melted and bubbly.
Remove from oven and let it cool for a few minutes before serving.
Garnish with chopped cilantro, if desired, and serve hot.

Notes

Make it spicy: Add diced jalapeños or use spicy salsa for extra heat.
Protein variation: Swap chicken for ground beef or turkey.
Storage: Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven at 325°F for best texture.
Serving suggestion: Pair with a simple side salad or Mexican rice for a complete meal.

Prep Time: 10 minutes
Cook Time: 30 minutes
Category: Dinner
Cuisine: Mexican, Tex-Mex

Nutrition

Calories: ~450 kcal
Fat: ~25g
Carbohydrates: ~30g
Protein: ~28g